Our Technology

Jurata's proprietary thin film formulations stabilize the three-dimensional structure of biologic materials in a thermostable film matrix, removing cold chain logistics in pharmaceutical fill/finish, distribution, storage, and delivery. Our thin films comprise a combination of pharmaceutical excipients that have been validated with many active pharmaceutical ingredients (API) and antigens, stabilizing biologics for three years at room temperature (25°C), as well as protecting embedded payloads at temperatures as low as -80°C and as high as 60°C.

Jurata's specializes in pharmaceutical formulation development in either a dried thin film presentation (shown to the right) or as a liquid formulation. In the film presentation, API or antigens can be stored in a low-moisture, compact presentation for long-term storage or administration via sublingual (under the tongue) or buccal (inside the cheek) routes. In a liquid presentation, API or antigens can be stored in a liquid format at room temperature for long periods of time and easily administered via injection or as an intranasal spray. 

While current pharmaceutical fill/finish processes require extremely low temperatures, incredibly large energy consumption, and can take up to 90 hours per cycle, Jurata's thin film formation process takes place at room temperature and requires less than 2 hours to complete. For other administration routes, Jurata's liquid formulations can be easily aliquoted into vials or syringes for injection or spray. Either system could be readily adapted in low- and middle-income countries, as well as low-resource regions in developed nations. 

Jurata's thin films and stabilizing formulations have been validated with: 

· Live Recombinant Adenovirus

· Live Influenza 

· mRNA LNPs

· Live bacteria

· Antibodies

· Plasmid DNA

· Antibody-Enzyme Conjugates

· Adjuvants

…and more

If you would like to discuss any of our results or are interested in studying our thin film technology for your company's therapeutics, please contact us using the link below.